The Wound Healing Innovation research line at TR2Lab, directed by Ph.D. Marta Otero, focuses on developing personalized, advanced therapeutic strategies to improve the healing of chronic cutaneous wounds.
Our research combines translational approaches with in vitro and ex vivo models to investigate the biological mechanisms underlying impaired tissue repair. We also study the effectiveness of advanced biological therapies -such as autologous platelet-rich plasma (PRP) and punch skin grafting (PSG)- to enhance skin regeneration and re-epithelialization.
Our long-term goals are twofold. First, we aim to deepen the understanding of the fundamental biology of skin repair and regeneration, enabling the design of novel, targeted biological therapies. Second, we work to empower the Clinical Wound Unit, led by specialist nurses, to drive innovation in individualized treatments and improved organizational care processes, ultimately increasing healing rates for chronic wounds.
Team
Our last happenings
Organization of complex wound units in Spain. Consensus document, Vic, June 2025
Authors: Marta Ferrer-Solà*; Joan Enric Torra-Bou; Josep María Gómez-Roldán; Carme Minguillón-Cebrián; Èlia Gómez-Losada; Carme Marquilles-Bonet; Sandra Alexandre-Lozano; Pere Coca-Alves; Nahikari Peñafiel-Herrera; Marta Casals-Zorita; Clara Masó-Albareda; Mariona Espaulella Ferrer; Joan Espaulella Panicot Gerokomos 2026;37(1):53-57 doi: S1134-928X2026000100009 Abstract: T his article presents the consensus reached by a group of [...]
The diagnostic accuracy of HE4 in the differential diagnosis of pleural effusions.
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, la-Torre ND, Bosch-Presegué L, Otero-Viñas M, Catot S, Crespo-Casal M, Rives-Jimenez J, Arnau A, Costa R, Cugat JR, Gonzalez-Sánchez F, Pla-Salas X, Sant F. Clin Chim Acta. 2025 Jan 30;566:120027. doi:10.1016/j.cca.2024.120027 Read More Abstract Background: Pleural effusions are [...]
Utility of human epididymis protein 4 in the differential diagnosis of ascites
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, de-la-Torre N, Trujillo G, Estivill D, Álvarez-González MA, Bosch L, Otero-Viñas M, Bergós C, Catot S, Ruiz-Hidalgo D, Ros S, Sant F Clin Biochem. 2023 Oct;120:110645. doi:10.1016/j.clinbiochem.2023.110645. Read More Abstract Background and aims: Human epididymal protein 4 [...]
