The Wound Healing Innovation research line at TR2Lab, directed by Ph.D. Marta Otero, focuses on developing personalized, advanced therapeutic strategies to improve the healing of chronic cutaneous wounds.
Our research combines translational approaches with in vitro and ex vivo models to investigate the biological mechanisms underlying impaired tissue repair. We also study the effectiveness of advanced biological therapies -such as autologous platelet-rich plasma (PRP) and punch skin grafting (PSG)- to enhance skin regeneration and re-epithelialization.
Our long-term goals are twofold. First, we aim to deepen the understanding of the fundamental biology of skin repair and regeneration, enabling the design of novel, targeted biological therapies. Second, we work to empower the Clinical Wound Unit, led by specialist nurses, to drive innovation in individualized treatments and improved organizational care processes, ultimately increasing healing rates for chronic wounds.
Team
Our last happenings
TR2Lab Invited at Congresso de Feridas Guarda 2026
Clara Masó Albareda, PhD student at TR2Lab, was invited to participate in the Congresso de Feridas Guarda 2026, held in Guarda, Portugal, on 14–15 October 2026. As part of the scientific programme, Clara delivered an invited lecture in the session “Tempo da Inovação – Hot Topics”, where she [...]
Exploring the Potential of Phygital Bone as a Synthetic Surrogate for Forensic Bone Trauma
Authors: Crespo-Santiago, J; Jordana, X; Gesualdo, M; Álvarez, A; Mallafré, H; Otero-Viñas, M; Rzymelka V; Andreu C; Garrido X; Schwab N; Galtés I. Exploring the potential of Phygital Bone as a synthetic surrogate for forensic bone trauma. Scientific Reports, 2026. DOI: https://doi.org/10.21203/rs.3.rs-10206802/v1 Keywords: Health sciences/Anatomy; Physical sciences/Engineering; Physical sciences/Materials science; [...]
Phygital Bone: A biomimetic parametric model to 3D-printing human bone surrogates.
Authors: Crespo-Santiago, J; Jordana, X; Gesualdo, M; Álvarez, A; Mallafré, H; Wückert, A; Fradera, M; Otero-Vinas, M. Results in Engineering, 2026. DOI: https://doi.org/10.1016/j.rineng.2026.110448 Keywords: Biomimetic design; Algorithm-aided design; Parametric modeling; 3D-printing; Bone surrogate; Biomechanics Funding: AEI Clusters Spanish Ministry for Industry and Tourism (AEI-010500–2024–18), Llavor AGAUR Gencat (2023 LLAVOR [...]
