The Determinants of Arrhythmogenesis research line is led by Ph.D. Elisabet Selga Coma. Our team is devoted to deciphering the clinical, genetic, and lifestyle factors that influence cardiac health outcomes. We bring together our clinical and molecular expertise to delineate a comprehensive picture of arrhythmogenic events with emphasis in their etiology and potential treatments.
Our current focus is, on one side, on establishing the more prevalent risk factors associated with unexplained sudden cardiac death and the role of mental pathologies in this context. On the other side, we aim to shed light on the multidimensional nature of atrial fibrillation by integrating knowledge on the major clinical, biochemical, microbial and molecular determinants leading to this pathology. We also seek to design non-pharmacologic programs to reduce atrial fibrillation burden and to improve quality of life of overweight/obese patients.
Team
Our last happenings
Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders
Autors: Pardo M, Gregorio S, Montalban E, Pujadas L, Elias-Tersa A, Masachs N, Vílchez-Acosta A, Parent A, Auladell C, Girault JA, Vila M, Nairn AC, Manso Y, Soriano E. Front Cell Neurosci. 2023 Apr 20;17:1143319 doi: 10.3389/fncel.2023.1143319 Read More Abstract: In addition to neuronal migration, brain development, and [...]
A key amino acid site associated with rhodopsin mammal evolution to diurnal vision.
Authors: Fernández-Sampedro MA, Ramon E, Aguileta G, Bosch-Presegué L, Garriga P. Sci Rep. 2025 Dec 26;16(1):411 doi:10.1038/s41598-025-29872-9. Read More Abstract Rhodopsin is a photoreceptor protein found in the vertebrate retina used as a landmark for vision evolution studies at the molecular level. Here, we examined the biochemical and [...]
The diagnostic accuracy of HE4 in the differential diagnosis of pleural effusions.
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, la-Torre ND, Bosch-Presegué L, Otero-Viñas M, Catot S, Crespo-Casal M, Rives-Jimenez J, Arnau A, Costa R, Cugat JR, Gonzalez-Sánchez F, Pla-Salas X, Sant F. Clin Chim Acta. 2025 Jan 30;566:120027. doi:10.1016/j.cca.2024.120027 Read More Abstract Background: Pleural effusions are [...]
