Elisabet Selga Coma Archives - TR2Lab - Tissue Repair and Regeneration

Molecular autopsy identifies the NaV1.5 p.Leu96Pro variant causing sodium current loss-of-function in unexplained sudden cardiac death

Authors: Albert Rigat Pujolasa, Rebecca Martínez-Moreno, David Carreras, Yajaira Alvarado-Cervantes, Elisabet Selga, Ramon Brugada, Guillermo J. Pérez, Fabiana S. Scornik Forensic Science International: Genetics, 86 (2027) 103587 DOI: 10.1016/j.fsigen.2026.103587 Read More Abstract Molecular autopsy can identify candidate variants in unexplained sudden cardiac death (SUD), but functional evidence [...]

Generation of human induced pluripotent stem cell lines from relatives of an unexplained sudden cardiac death victim carrying a Brugada Syndrome-associated, SCN5A c.287 T>C, variant

Authors: Elisabet Selga, Rebecca Martínez-Moreno, Albert Rigat Pujolàs, Begoña Aran, Bernd Kuebler, Guillermo J. Pérez, Fabiana S. Scornik *, Ramon Brugada Stem Cell Research. 2026 DOI:10.1016/j.scr.2026.104071 Read More Abstract Patient-derived induced pluripotent stem cells (hiPSC) are a valuable approach to model cardiovascular diseases. We nucleofected non-integrating episomal vectors [...]