Research Line in Determinants of Arrhythmogenesis

TR2Lab at the 4th Lecture Series at the Paranimf of UVic-UCC

Laia Nogué Navarro, member of the TR2Lab research group, hosted and moderated the event and introduced Dr Narcís Bardalet, forensic physician, as part of the 4th Lecture Series at the Paranimf of UVic-UCC. The session, dedicated to historical memory, explored reflections on death and protocols for investigating mass graves, highlighting [...]

Molecular autopsy identifies the NaV1.5 p.Leu96Pro variant causing sodium current loss-of-function in unexplained sudden cardiac death

Authors: Albert Rigat Pujolasa, Rebecca Martínez-Moreno, David Carreras, Yajaira Alvarado-Cervantes, Elisabet Selga, Ramon Brugada, Guillermo J. Pérez, Fabiana S. Scornik Forensic Science International: Genetics, 86 (2027) 103587 DOI: 10.1016/j.fsigen.2026.103587 Read More Abstract Molecular autopsy can identify candidate variants in unexplained sudden cardiac death (SUD), but functional evidence [...]

Generation of human induced pluripotent stem cell lines from relatives of an unexplained sudden cardiac death victim carrying a Brugada Syndrome-associated, SCN5A c.287 T>C, variant

Authors: Elisabet Selga, Rebecca Martínez-Moreno, Albert Rigat Pujolàs, Begoña Aran, Bernd Kuebler, Guillermo J. Pérez, Fabiana S. Scornik *, Ramon Brugada Stem Cell Research. 2026 DOI:10.1016/j.scr.2026.104071 Read More Abstract Patient-derived induced pluripotent stem cells (hiPSC) are a valuable approach to model cardiovascular diseases. We nucleofected non-integrating episomal vectors [...]

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