The Wound Healing Innovation research line at TR2Lab, directed by Ph.D. Marta Otero, focuses on developing personalized, advanced therapeutic strategies to improve the healing of chronic cutaneous wounds.
Our research combines translational approaches with in vitro and ex vivo models to investigate the biological mechanisms underlying impaired tissue repair. We also study the effectiveness of advanced biological therapies -such as autologous platelet-rich plasma (PRP) and punch skin grafting (PSG)- to enhance skin regeneration and re-epithelialization.
Our long-term goals are twofold. First, we aim to deepen the understanding of the fundamental biology of skin repair and regeneration, enabling the design of novel, targeted biological therapies. Second, we work to empower the Clinical Wound Unit, led by specialist nurses, to drive innovation in individualized treatments and improved organizational care processes, ultimately increasing healing rates for chronic wounds.

Team
Our last happenings
The diagnostic accuracy of HE4 in the differential diagnosis of pleural effusions.
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, la-Torre ND, Bosch-Presegué L, Otero-Viñas M, Catot S, Crespo-Casal M, Rives-Jimenez J, Arnau A, Costa R, Cugat JR, Gonzalez-Sánchez F, Pla-Salas X, Sant F. Clin Chim Acta. 2025 Jan 30;566:120027. doi:10.1016/j.cca.2024.120027 Read More Abstract Background: Pleural effusions are [...]
Utility of human epididymis protein 4 in the differential diagnosis of ascites
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, de-la-Torre N, Trujillo G, Estivill D, Álvarez-González MA, Bosch L, Otero-Viñas M, Bergós C, Catot S, Ruiz-Hidalgo D, Ros S, Sant F Clin Biochem. 2023 Oct;120:110645. doi:10.1016/j.clinbiochem.2023.110645. Read More Abstract Background and aims: Human epididymal protein 4 [...]
Cultural Adaptation and Psychometric Assessment of the Catalan Version of the Wound‐QoL‐17
Authors: Casals-Zorita M*, Masó-Albareda C, Palacio-Arronis N, Ghanam-Zaidan O, Puigoriol-Juvanteny E, Otero-Viñas M, Janke TM, Ferrer-Solà M, Sarri E. International Wound Journal. 2026. 23(1), num:70806 DOI:10.1111/iwj.70806 Read More Abstract Complex chronic wounds are an increasing health concern, affecting individuals both physically and psychologically. To measure the quality [...]










