GRANT

Original Title (English): “Phygital Human Bone.”

Reference: 2023 LLAV 00055

Principal Investigador: Marta Otero Viñas

TR2Lab research team members: Juan Crespo Santiago Xavier Jordana Comín

Funded by: AGAUR – Generalitat de Catalunya

Biotechnological and biomedical fields frequently use biological bones for their significant representation of living bone. Yet, these come with challenges: costs, degradation, disease transmission, ethical concerns, storage difficulties, and biological variability. Hence, synthetic bone surrogates emerge as a solution but currently have limitations in replicating the mechanical attributes of natural bone, primarily due to missing precise microarchitecture imitations.

Understanding this gap, our initiative bridges the technological disparity by developing a synthetic bone tissue model, meticulously replicating the human bone tissue microstructure. This endeavor employs algorithm-aided design (AAD) to echo authentic architectural and biomechanical attributes. As a product, our creation, the Phygital Human Bone (PHyB), stands as a prototype that has displayed promising results in preliminary biomechanical tests, reflecting the intricate processes of microdamage propagation observed in genuine bone tissue