Laia Bosch-Presegué
Coordinator of the Epigenetics and tissue transformation research line in the TR2Lab
Email: laia.bosch@uvic.cat
ORCID: 0000-0001-8025-2416
Scientific Profile: URECERCA
Professor of the Faculty of Health Sciences and Welfare at the University of Vic – Central University of Catalonia.
She did his Ph.D. in the Professor Pere Garriga laboratory at Universitat Politècnica de Catalunya. During her PhD studies, she focused on the structure-function relationships of the prototype of G-protein-coupled receptors Rhodopsin and in the molecular basis of disease associated with mutations in this important receptor causing retinal degenerations, like retinitis pigmentosa.
From 2008 to 2018, she joined as a researcher in the Chromatin Biology group led by Ph.D. Alex Vaquero, in the Department of Epigenetics and Cancer Biology Program at IDIBELL. Her primary research interest was to understand the mechanisms that rule Chromatin dynamics and in particular, how the post-translational modifications of the N-terminal tails of histones are important for ensuring a proper control of chromatin functions interplay with the rest of chromatin machinery to keep a healthy and efficient Chromatin organization.
After her incorporation as a Professor at the University of Vic – Central University of Catalonia, Ph.D. Laia Bosch-Presegué has joined the Research Line of Epigenetics and tissue transformation in TR2Lab. Currently, her research is focused on studying epigenetic events in different pathologies and how different interventions can prevent their appearance, improve symptoms or contribute to their healing.
My last happenings:
Exploiting Hormesis for Plasma-treated Hydrogel Therapeutic platforms (HormeTic)
Subprojects: Subproject 1: "Exploiting Hormesis for plasma-treated hydrogel therapeutic platforms for cancer treatment (HormOnc)". Subproject 2: "Exploiting Hormesis for plasma-treated hydrogel therapeutic platforms for Healing of complex cutaneous wounds (HormHeal)". Original Title (English): Exploiting Hormesis for plasma-treated hydrogel therapeutic platforms for Healing of complex cutaneous wounds (HormHeal). Objective: Innovating in the healing of complex wounds. TR2Lab research team members: Albert Espona-Noguera (Principal Investigator). Cristina Canal (PI1 of Subproject 1) & Francesco Tampieri (PI2 of Subproject 1). Members of TR2Lab who participate in this project: Elisabet Sarri, Laia Bosch, Gemma Sangüesa, Francesc Sant Masoliver, Cristina Martin Mancera, David Benito Guasch, Clara Masó [...]
Vocations Born in the Laboratory: Biomedical Workshops for Upper Secondary Students
The Biomedical Workshops are a well-established scientific outreach initiative promoted by TR2Lab within the framework of the Educational Biomedicine Program. The program is aimed at upper secondary (baccalaureate) students and seeks primarily to strengthen the bridge between scientific education at school level and university studies in the biomedical field. At the same time, these workshops serve as a valuable platform to bring biomedical sciences closer to young people, stimulate emerging scientific vocations, and channel students’ curiosity and interest in research. In this edition, 171 students from secondary schools in Osona and Vallès took part in the workshops, providing highly positive [...]
A key amino acid site associated with rhodopsin mammal evolution to diurnal vision.
Authors: Fernández-Sampedro MA, Ramon E, Aguileta G, Bosch-Presegué L, Garriga P. Sci Rep. 2025 Dec 26;16(1):411 doi:10.1038/s41598-025-29872-9. Read More Abstract Rhodopsin is a photoreceptor protein found in the vertebrate retina used as a landmark for vision evolution studies at the molecular level. Here, we examined the biochemical and functional performance of modern rhodopsin from three different mammal species- bovine, murine and human-to analyze their visual pigment evolutionary relationships. We selected these species for their relevance in vision research, their different position on the phylogenetic tree and their diverse ethology regarding nocturnal (mouse) and diurnal (bovine and human) life. [...]
