Juan Crespo Santiago

Coordinator of the Generative design strategies for tissue engineering research line in TR2Lab

ORCID: 0000-0002-0762-9325

Scientific Profile: URECERCA

Juan Crespo is associate professor at the Industrial Design Engineering BSc at Elisava University School of Design and Engineering UVIC-UCC (Barcelona), and research leader of Generative design strategies for tissue engineering research line at Tissue Repair and Regeneration Laboratory (TR2Lab) at UVIC-UCC. His research focuses on exploring the potential of biomedicine, generative design and additive manufacturing to create new strategies for tissue regeneration. He currently leads the projects 3D BONE BIOTEC funded by AEI (Ministerio de Industria y Turismo) and PHYGITAL HUMAN BONE funded by LLAVOR (AGAUR).

Juan Crespo holds a PhD in Biomedicine awarded Cum Laude in 2016, from the University of Barcelona (Spain) on Development of biomimetic human iPS-derived myocardial grafts. A MSc in Biomedical Engineering on Development of nano-fibered stimulating scaffolds, from the University of Barcelona & Polytechnic University of Catalonia (Spain), a BSc in Industrial Design Engineering from Elisava University School of Design and Engineering UVIC-UCC (Spain) and a BA in Design from the Polytechnic University of Catalonia (Spain).

Previously, during the completion of his PhD he worked as a predoctoral researcher at the Induced Pluripotent Stem Cells (iPSC) Potency group with Dr. Ángel Raya, at the Institute of Engineering of Catalonia (IBEC), Barcelona. In 2016 he became a collaborating professor at Elisava UVIC-UCC, and in 2019 he became an associate professor and head of the Design and Materials Area of the same institution. In 2021 he founded the Biolab to promote bioengineering research and began his own research line at the same institution. The same year he joined the TR2Lab UIVIC-UCC as Senior Researcher, where he currently continues to expand his research in bone tissue engineering.

My last happenings:

From Subversive Labs to Biodesign Literate Curricula: Rethinking Biodesign Education

Authors: Orcajada M. A., Rognoli V, Crespo-Santiago J, Ordóñez I. Biotechnology design, Cambridge University Press, 2026. Results in Engineering, 2026. DOI:https://doi.org/10.1017/S2977905726100390 Keywords: biodesign; biodesign literacy; subversive; labs; education. Funding: This research was partially funded by the Erasmus+ programme Centres of Vocational Excellence, “Transforming Education Area and Competency Hub for Sustainable Development” (project acronym: TEACH4SD). The content of this publication does not reflect the official opinion of the European Union; responsibility for the information and views expressed lies entirely with the author(s). Read More Biodesign has gained prominence over the past two decades yet remains conceptually hazy and institutionally [...]

November 6, 2026|

Exploring the Potential of Phygital Bone as a Synthetic Surrogate for Forensic Bone Trauma

Authors: Crespo-Santiago, J; Jordana, X; Gesualdo, M; Álvarez, A; Mallafré, H; Otero-Viñas, M; Rzymelka V; Andreu C; Garrido X; Schwab N; Galtés I. Exploring the potential of Phygital Bone as a synthetic surrogate for forensic bone trauma. Scientific Reports, 2026. DOI: https://doi.org/10.21203/rs.3.rs-10206802/v1 Keywords: Health sciences/Anatomy; Physical sciences/Engineering; Physical sciences/Materials science; Health sciences/Medical research; Bone trauma; Synthetic bone surrogate; Forensic trauma reconstruction; Bone biomechanics; 3D-printed bone model. Funding: This research was funded by: AEI Clusters Spanish Ministry for Industry and Tourism (AEI-010500-2024-18), Llavor AGAUR Gencat (2023 LLAVOR 0005), and Proyectos de Generación de Conocimiento, Agencia Estatal de Investigación (PID2021-124112NB-100). Read More [...]

November 2, 2026|

Phygital Bone: A biomimetic parametric model to 3D-printing human bone surrogates.

Authors: Crespo-Santiago, J; Jordana, X; Gesualdo, M; Álvarez, A; Mallafré, H; Wückert, A; Fradera, M; Otero-Vinas, M. Results in Engineering, 2026. DOI: https://doi.org/10.1016/j.rineng.2026.110448 Keywords: Biomimetic design; Algorithm-aided design; Parametric modeling; 3D-printing; Bone surrogate; Biomechanics Funding: AEI Clusters Spanish Ministry for Industry and Tourism (AEI-010500–2024–18), Llavor AGAUR Gencat (2023 LLAVOR 0005), and Proyectos de Generación de Conocimiento, Agencia Estatal de Investigación (PID2021–124112NB-100). Read More Accurate human bone surrogates are essential for biomechanical research. Existing commercial models provide limited control over microarchitectural features. In this study, we present Phygital Bone (PHyB), a biomimetic and fully customizable 3D-printed bone surrogate [...]

October 29, 2026|