Elisabet Sarri Plans

Early Impairment of Lung Mechanics in a Murine Model of Marfan Syndrome.

ARTICLE. Uriarte JJ, Meirelles T, Gorbenko Del Blanco D, Nonaka PN, Campillo N, Sarri E, Navajas D, Egea G, Farré R. PLoS One. 2016 Mar 22;11(3):e0152124. doi: 10.1371/journal.pone.0152124. eCollection 2016. Abstract. Early morbidity and mortality in patients with Marfan syndrome (MFS) -a connective tissue disease caused by mutations in fibrillin-1 [...]

Vascular smooth muscle cell phenotypic changes in patients with Marfan syndrome

ARTICLE. Crosas-Molist E, Meirelles T, López-Luque J, Serra-Peinado C, Selva J, Caja L, Gorbenko Del Blanco D, Uriarte JJ, Bertran E, Mendizábal Y, Hernández V, García-Calero C, Busnadiego O, Condom E, Toral D, Castellà M, Forteza A, Navajas D, Sarri E, Rodríguez-Pascual F, Dietz HC, Fabregat I, Egea G. Arterioscler Thromb [...]

PLCγ1 participates in protein transport and diacylglycerol production triggered by cargo arrival at the Golgi.

ARTICLE. Sicart A, Katan M, Egea G, Sarri E. Traffic. 2015 Mar;16(3):250-66. Abstract. Diacylglycerol (DAG) is required for membrane traffic and structural organization at the Golgi. DAG is a lipid metabolite of several enzymatic reactions present at this organelle, but the mechanisms by which they are regulated are still unknown. Here, we [...]

Chronic activation of the TGF-β signaling is responsible for Vascular Smooth Muscle phenotypic changes in patients with Marfan syndrome

PRESENTATION IN CONGRESS. Eva Crosas-Molist, Thayna Meirelles, Darya Gorbenko del Blanco, Judit López-Luque, Carla Serra-Peinado, Javier Selva, Juan José Uriarte, Laia Caja, Yolanda Mendizábal, Vanessa Hernández, Oscar Busnadiego, David Toral, Manel Castellà, Daniel Navajas, Alberto Forteza, Sarri E, Fernando Rodríguez-Pascual, Harry D. Dietz, Isabel Fabregat, Gustavo Egea. Chronic activation of the TGF-β [...]

Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway.

ARTICLE. Gutiérrez-Martínez E, Fernández-Ulibarri I, Lázaro-Diéguez F, Johannes L, Pyne S, Sarri E, Egea G. J Cell Sci. 2013 Jun 15;126(Pt 12):2641-55. Abstract. The inhibition of phosphatidic acid phosphatase (PAP) activity by propanolol indicates that diacylglycerol (DAG) is required for the formation of transport carriers at the Golgi and for [...]

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