Elisabet Sarri Plans

PLCγ1 participates in protein transport and diacylglycerol production triggered by cargo arrival at the Golgi.

ARTICLE. Sicart A, Katan M, Egea G, Sarri E. Traffic. 2015 Mar;16(3):250-66. Abstract. Diacylglycerol (DAG) is required for membrane traffic and structural organization at the Golgi. DAG is a lipid metabolite of several enzymatic reactions present at this organelle, but the mechanisms by which they are regulated are still unknown. Here, we [...]

2021-11-26T11:16:20+01:00March 1, 2015|2015, Articles, Articles 2015, Elisabet Sarri Plans 2015, General|

Chronic activation of the TGF-β signaling is responsible for Vascular Smooth Muscle phenotypic changes in patients with Marfan syndrome

PRESENTATION IN CONGRESS. Eva Crosas-Molist, Thayna Meirelles, Darya Gorbenko del Blanco, Judit López-Luque, Carla Serra-Peinado, Javier Selva, Juan José Uriarte, Laia Caja, Yolanda Mendizábal, Vanessa Hernández, Oscar Busnadiego, David Toral, Manel Castellà, Daniel Navajas, Alberto Forteza, Sarri E, Fernando Rodríguez-Pascual, Harry D. Dietz, Isabel Fabregat, Gustavo Egea. Chronic activation of the TGF-β [...]

2021-12-09T10:05:25+01:00January 1, 2014|2014, Elisabet Sarri Plans 2014, General, Meetings, Meetings 2014|

Lipid phosphate phosphatase 3 participates in transport carrier formation and protein trafficking in the early secretory pathway.

ARTICLE. Gutiérrez-Martínez E, Fernández-Ulibarri I, Lázaro-Diéguez F, Johannes L, Pyne S, Sarri E, Egea G. J Cell Sci. 2013 Jun 15;126(Pt 12):2641-55. Abstract. The inhibition of phosphatidic acid phosphatase (PAP) activity by propanolol indicates that diacylglycerol (DAG) is required for the formation of transport carriers at the Golgi and for [...]

Regulation and alteration in the membrane trafficking, extracellular matrix assembly and TGFB signaling in cellular models of Marfan syndrome.

GRANT. Project information. Original Title: Regulación y Alteración en el tráfico de membranas, ensamblaje de la matriz extracelular y señalización del TGFβ en modelos celulares del Síndrome de Marfan. Principal Investigador: Gustavo Egea TR2 Lab partner: Elisabet Sarri Plans Funded by: Ministerio Economia y Competitividad. Ref: BFU2012-33932. Period: 2013/2016

2018-10-28T10:41:25+01:00January 1, 2013|2013, Elisabet Sarri Plans 2013, General, Projects, Projects 2013|

Development of a protocol to produce extracellular matrix from vascular smooth muscle cells of a murine model of Marfan syndrome to evaluate future therapeutic strategies

GRANT. Project information. Original Title: Development of a protocol to produce extracellular matrix from vascular smooth muscle cells of a murine model of Marfan syndrome to evaluate future therapeutic strategies. Principal Investigador: Elisabet Sarri Plans Funded by: Fundació La Marató de TV3 (Transplantaments i Regeneració de Teixits), Ref:122310 Period: 2013/2015

2018-10-28T10:40:48+01:00January 1, 2013|2013, Elisabet Sarri Plans 2013, General, Projects, Projects 2013|
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