Articles 2015

Transforming Growth Factors β (TGF-β) Isoforms in Wound Healing and Fibrosis.

ARTICLE. Lichtman MK, Otero-Vinas M, Falanga V. Wound Repair Regen. 2016 Mar;24(2):215-22. doi: 10.1111/wrr.12398. Abstract. Scar formation, with persistent alteration of the normal tissue structure, is an undesirable and significant result of both wound healing and fibrosing disorders. There are few strategies to prevent or to treat scarring. The transforming [...]

Vascular smooth muscle cell phenotypic changes in patients with Marfan syndrome

ARTICLE. Crosas-Molist E, Meirelles T, López-Luque J, Serra-Peinado C, Selva J, Caja L, Gorbenko Del Blanco D, Uriarte JJ, Bertran E, Mendizábal Y, Hernández V, García-Calero C, Busnadiego O, Condom E, Toral D, Castellà M, Forteza A, Navajas D, Sarri E, Rodríguez-Pascual F, Dietz HC, Fabregat I, Egea G. Arterioscler Thromb [...]

Liver Enzymes and Lipid Levels in Patients With Lipodermatosclerosis and Venous Ulcers Treated With a Prototypic Anabolic Steroid (Stanozolol): A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial.

ARTICLE. Carson P, Hong CJ, Otero-Vinas M, Arsenault EF, Falanga V. Int J Low Extrem Wounds. 2015 Mar;14(1):11-8. Abstract. Anabolic steroids have been used to treat lower extremity ulcerations, including venous and cryofibrinogenemic ulcers and lipodermatosclerosis (LDS). Yet there have been no studies to determine the severity and reversibility of side effects [...]

PLCγ1 participates in protein transport and diacylglycerol production triggered by cargo arrival at the Golgi.

ARTICLE. Sicart A, Katan M, Egea G, Sarri E. Traffic. 2015 Mar;16(3):250-66. Abstract. Diacylglycerol (DAG) is required for membrane traffic and structural organization at the Golgi. DAG is a lipid metabolite of several enzymatic reactions present at this organelle, but the mechanisms by which they are regulated are still unknown. Here, we [...]

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