Our research involves the application and development of computational and data science methods for approaching biomedical problems, with the support of wet-lab experiments when required. The Bi-squared research activities are structured along three main research lines:

Genomics and metagenomics

  • Methods for omics data integration in biomedical projects
  • Transcriptomics and evolution in entomology
  • New algorithms for microbiome analysis
  • Microbiome analysis in human health and ecology studies

Computational biochemistry

  • CBB Lab: Free energy calculations for protein structure-function relationships.
  • RareVariants Lab: Effect of mutations in proteins structure and function.

Quantitative bioimaging

  • Data science for bioimaging
  • Advanced bioimaging for molecular and cell biology
  • Computer vision and computational neuroscience
  • Modeling of biological processes