The Understanding Breast Cancer: cell and tissue microenvironment crosstalk (UBC) research line is leaded by Ph.D. Gemma Fuster and is centered to better molecularly know ductal carcinoma in situ in breast cancer, the most common pre-invasive form of breast cancer, and its transition process to invasive breast cancer, taking into account microenvironment influences.
Our research project focuses on understanding the role of the microenvironment (including both tumor crosstalk and influences) since it is crucial to understand and predict tumour evolution and treatment. The scientific and technical efforts made to better know crosstalk between these two compartments in tumor process can improve also the knowledge of tissue regeneration context cell’s relationship, contributing to other research TR2lab lines.
Team
Research line coordinator: Ph.D. Gemma Fuster Orellana
Doctoral Candidates:
- Conceiçao Pinto Da Silva
Our last happenings
Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders
Autors: Pardo M, Gregorio S, Montalban E, Pujadas L, Elias-Tersa A, Masachs N, Vílchez-Acosta A, Parent A, Auladell C, Girault JA, Vila M, Nairn AC, Manso Y, Soriano E. Front Cell Neurosci. 2023 Apr 20;17:1143319 doi: 10.3389/fncel.2023.1143319 Read More Abstract: In addition to neuronal migration, brain development, and [...]
A key amino acid site associated with rhodopsin mammal evolution to diurnal vision.
Authors: Fernández-Sampedro MA, Ramon E, Aguileta G, Bosch-Presegué L, Garriga P. Sci Rep. 2025 Dec 26;16(1):411 doi:10.1038/s41598-025-29872-9. Read More Abstract Rhodopsin is a photoreceptor protein found in the vertebrate retina used as a landmark for vision evolution studies at the molecular level. Here, we examined the biochemical and [...]
The diagnostic accuracy of HE4 in the differential diagnosis of pleural effusions.
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, la-Torre ND, Bosch-Presegué L, Otero-Viñas M, Catot S, Crespo-Casal M, Rives-Jimenez J, Arnau A, Costa R, Cugat JR, Gonzalez-Sánchez F, Pla-Salas X, Sant F. Clin Chim Acta. 2025 Jan 30;566:120027. doi:10.1016/j.cca.2024.120027 Read More Abstract Background: Pleural effusions are [...]
