Gemma Fuster Orellana
Coordinator of the Understanding breast cancer research line
Email: gemma.fuster@uvic.cat
ORCID: 0000-0002-4501-2422
Scientific Profile: URECERCA
She is a senior researcher and her scientific career is focused on molecular and cellular biology, areas that have allowed her to study mainly cancer. She worked on different topics, all of them related to health, including cancer cachexia and breast cancer (BC). She is author of 34 indexed publications, some of which are first, last and corresponding authors in high impact journals, mainly in the field of oncology. She disseminated her results at national and international conferences, and as an invited speaker at university-research centres and medical institutes. She participated in multiple competitive projects as a collaborator and as principal investigator. She enjoyed a pre-doctoral FPI grant, and she received two postdoctoral grants (Juan de la Cierva/Sara Borrell) and an extraordinary PhD award at UB. She supervised 7 TFMs, 3 TFGs, and 2 doctoral theses. Her main scientific interest is focused on the molecular understanding of the most frequent pre-invasive lesions (DCIS) in CM, from the approach of cancer cells and the tumour microenvironment, focusing on the role of neuronal factors. Currently, she is collaborating in one of the TR2Lab research group projects about mechanisms of tissue repair and regeneration.
My last happenings:
Gemma Fuster presented the results of La Marató TV3 project about breast cancer resistance in ASEICA 40th anniversary Congress.
The poster communication has been presented in ASEICA 40th anniversary Congress in La Coruña from 14 to 16th november. This work has been the result of a La Marató TV3 project in collaboration with Hospital Germans Trias i Pujol (IGTP) i Institut de Ciències Fotòniques (ICFO). The results of the poster identified a molecular signature as a prediction biomarkers of therapy in breast cancer patients. The original title of the poster communication is NR4A1/3 and HBB as new predictive biomarkers of neoadjuvant responses in breast cancer patients.
In Vitro and In Vivo Effects of the Combination of Polypurine Reverse Hoogsteen Hairpins against HER-2 and Trastuzumab in Breast Cancer Cells
In Vitro and In Vivo Effects of the Combination of Polypurine Reverse Hoogsteen Hairpins against HER-2 and Trastuzumab in Breast Cancer Cells Authors: López-Aguilar, Ester; Fernandez-Nogueira, Patrícia; Fuster, Gemma; Carbó, Neus; Ciudad, Carlos; Noé, Veronica. Abstract: Therapeutic oligonucleotides are powerful tools for the inhibition of potential targets involved in cancer. We describe the effect of two Polypurine Reverse Hoogsteen (PPRH) hairpins directed against the ERBB2 gene, which is overexpressed in positive HER-2 breast tumors. The inhibition of their target was analyzed by cell viability and at the mRNA and protein levels. The combination of [...]
Animal model of the chorioallantoic membrane in chicken embryo: From microbiological to oncological research
On April 20th, Dr. Gemma Fuster, member of the Understanding Breast Cancer research group, participated in the technological seminars organized by the Faculty of Pharmacy and Food Science. The seminar was about the chicken chorioallantoic membrane model, from microbiological to oncological research. The CAM model is a very attractive in vivo model for many fields from microbiology, through embryonic and vascular development, and also in the field of oncology. It is a very powerful model thanks to its simplicity, high reproducibility, speed and low cost that allows from the approach in basic and pre-clinical research to applications as attractive [...]
