Juan Crespo Santiago

Coordinator of the Engineering, design & living systems research line in TR2Lab

ORCID: 0000-0002-0762-9325

Scientific Profile: URECERCA

Juan Crespo is associate professor at the Industrial Design Engineering BSc at Elisava University School of Design and Engineering UVIC-UCC (Barcelona), and research leader of Design, Engineering & Living Systems group at Tissue Repair and Regeneration Laboratory (TR2Lab) at UVIC-UCC. His research focuses on exploring the potential of biomedicine, generative design and additive manufacturing to create new strategies for tissue regeneration. He currently leads the projects 3D BONE BIOTEC funded by AEI (Ministerio de Industria y Turismo) and PHYGITAL HUMAN BONE funded by LLAVOR (AGAUR).

Juan Crespo holds a PhD in Biomedicine awarded Cum Laude in 2016, from the University of Barcelona (Spain) on Development of biomimetic human iPS-derived myocardial grafts. A MSc in Biomedical Engineering on Development of nano-fibered stimulating scaffolds, from the University of Barcelona & Polytechnic University of Catalonia (Spain), a BSc in Industrial Design Engineering from Elisava University School of Design and Engineering UVIC-UCC (Spain) and a BA in Design from the Polytechnic University of Catalonia (Spain).

Previously, during the completion of his PhD he worked as a predoctoral researcher at the Induced Pluripotent Stem Cells (iPSC) Potency group with Dr. Ángel Raya, at the Institute of Engineering of Catalonia (IBEC), Barcelona. In 2016 he became a collaborating professor at Elisava UVIC-UCC, and in 2019 he became an associate professor and head of the Design and Materials Area of the same institution. In 2021 he founded the Biolab to promote bioengineering research and began his own research line at the same institution. The same year he joined the TR2Lab UIVIC-UCC as Senior Researcher, where he currently continues to expand his research in bone tissue engineering.

My last happenings:

3D BONE BIOTEC

GRANT Original Title (English): “3D BONE BIOTEC” Reference: AEI-010500-2024-18 PI: Juan Crespo Santiago Participants: ELISAVA UVIC-UCC, Fundació CIM UPC, PERDIGÓ, DAN*NA, Cluster de Materials Avançats de Catalunya, Cluster CataloniaBio & HealthTech. Funded by: Ministerio de Industria y Turismo A research project that will generate algorithm-aided designed human bone models suitable to be manufactured using a new ad-hoc developed 3D printing technology with advanced biocompatible substrates. Based on these 3D biomimetic human bone models, the project aims to design a novel 3D printing system based on DLP technology, that may be able to manufacture biomimetic human bone samples with improved mechanical behavior. [...]

November 12, 2024|

Oozing: An accessible technique to create 3D-printed scaffolds suitable for tissue engineering

Oozing: An accessible technique to create 3D-printed scaffolds suitable for tissue engineering Authors: Juan Crespo Santiago, Luis M. Delgado, Rafa Madariaga, Laia Millan, Oriol Chico, Pau Oliver, Román Pérez, Marta Otero Viñas Abstract Tissue-engineered constructs require mimicking the extracellular matrix microenvironment of native tissue for better promoting cell growth. Commercial three-dimensional (3D) printers provide a versatile platform to fabricate tissue models,but they possess certain constraints regarding the reproduction of natural tissue structures due to the limited functionality of current slicing strategies and hardware. In this study, we present a new approach to 3D-printing polylactic [...]

November 8, 2024|

Phygital Human Bone

GRANT Original Title (English): “Phygital Human Bone.” Reference: 2023 LLAV 00055 Principal Investigador: Marta Otero Viñas TR2Lab research team members: Juan Crespo Santiago Xavier Jordana Comín Funded by: AGAUR – Generalitat de Catalunya Biotechnological and biomedical fields frequently use biological bones for their significant representation of living bone. Yet, these come with challenges: costs, degradation, disease transmission, ethical concerns, storage difficulties, and biological variability. Hence, synthetic bone surrogates emerge as a solution but currently have limitations in replicating the mechanical attributes of natural bone, primarily due to missing precise microarchitecture imitations. Understanding this gap, our initiative bridges [...]

January 18, 2024|