Xavier Rovira 2018

A Light-Controlled Allosteric Modulator Unveils a Role for mGlu4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex

ARTICLE. Bossi, S., Helleringer, R., Galante, M., Monlleó, E., Trapero, A., Rovira, X., … McLean, H. (2018). A Light-Controlled Allosteric Modulator Unveils a Role for mGlu4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex. Frontiers in Cellular Neuroscience, 12, 449. https://doi.org/10.3389/fncel.2018.00449 Abstract Metabotropic glutamate receptors (mGlus) are [...]

  • Fotofarmacology Symposium

The photofarmacology symposium establishes in Vic the basis for the future application of drugs regulated by light in people

The leading international figures in the photopharmacology field met 1-2 November in Vic, at the second international symposium to be held on this emerging branch of science, which uses light to control the activity of medication. Around 130 people from universities and research centres in 15 different countries participated in [...]

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

ARTICLE. Amélie S.Tora, Xavier Rovira, Anne-Marinette Cao, Alexandre Cabayé, Linnéa Olofsson, Fanny Malhaire, Pauline Scholler, Hayeon Baik, AnnVan Eeckhaut, Ilse Smolders, Philippe Rondard, Emmanuel Margeat, Francine Acher, Jean-Philippe Pin, Cyril Goudet. Neuropharmacology. 2018 Sep 15;140:275-286. doi: 10.1016/j.neuropharm.2018.08.011. Epub 2018 Aug 11.   Abstract Due to the essential roles of glutamate, detection and response to a large range of extracellular concentrations of this excitatory amino acid are [...]

  • SGR 2018

TR2Lab has been recognized as an Emergent research group (SGE) by the SGR2017 Catalonia Government

GRANT. Project information. TR2Lab has been recognized as an Interinstitutional Emergent research group (SGE) in the SGR2017 call of the  Catalonia Government. The purpose of this grants is to support research groups (SGR) that develop research in Catalonia in the different scientific areas with the aim of boosting their activity [...]

  • Fotofarmacology Symposium

2nd International Symposium on Photopharmacology organized in UVic

Photopharmacology is an emerging branch of science based on the administration of a photosensitive compound combined with the irradiation of light to provide a high degree of local and temporal control of the activity of a compound, which makes it useful for therapeutic applications and research tool. It is a [...]

Go to Top