Xavier Rovira

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

ARTICLE. Amélie S.Tora, Xavier Rovira, Anne-Marinette Cao, Alexandre Cabayé, Linnéa Olofsson, Fanny Malhaire, Pauline Scholler, Hayeon Baik, AnnVan Eeckhaut, Ilse Smolders, Philippe Rondard, Emmanuel Margeat, Francine Acher, Jean-Philippe Pin, Cyril Goudet. Neuropharmacology. 2018 Sep 15;140:275-286. doi: 10.1016/j.neuropharm.2018.08.011. Epub 2018 Aug 11.   Abstract Due to the essential roles of glutamate, detection and response to a large range of extracellular concentrations of this excitatory amino acid are [...]

  • SGR 2018

TR2Lab has been recognized as an Emergent research group (SGE) by the SGR2017 Catalonia Government

GRANT. Project information. TR2Lab has been recognized as an Interinstitutional Emergent research group (SGE) in the SGR2017 call of the  Catalonia Government. The purpose of this grants is to support research groups (SGR) that develop research in Catalonia in the different scientific areas with the aim of boosting their activity [...]

  • Fotofarmacology Symposium

2nd International Symposium on Photopharmacology organized in UVic

Photopharmacology is an emerging branch of science based on the administration of a photosensitive compound combined with the irradiation of light to provide a high degree of local and temporal control of the activity of a compound, which makes it useful for therapeutic applications and research tool. It is a [...]

Shedding light on metabotropic glutamate receptors using optogenetics and photopharmacology

ARTICLE. Goudet C, Rovira X, Llebaria A. Rev Curr Opin Pharmacol doi: 10.1016/j.coph.2018.01.007 Abstract Metabotropic glutamate receptors (mGluRs) are a family of G protein-coupled receptors activated by glutamate, the main excitatory neurotransmitter of the mammalian central nervous system. These receptors are considered as potential therapeutic targets in many neurological diseases but a better [...]

  • Grünenthal Foundation

The “Cátedra Extraordinaria del Dolor” gives a prize to a study in which Xavier Rovira has participated for the second consecutive year.

Xavier Rovira, director of the research line in Molecular Photopharmacology in the TR2Lab, has participated in a study which has been awarded the Preclinical Research Award from “Cátedra Extraordinaria del Dolor” of the University of Salamanca – Grünenthal Foundation. This is the second consecutive year a work of Xavier Rovira [...]

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