Congratulations to Dr. Xavier Rovira, who has obtained a position as a senior researcher at the CSIC in Barcelona. TR2Lab bids farewell to our colleague Xavier Rovira who moves at the Dr. Amadeu Llaveria lab in Barcelona to continue his research project in molecular photopharmacology. TR2Lab thanks Dr. Rovira for [...]
ARTICLE. Xue L, Sun Q, Zhao H, Rovira X, Gai S, He Q, Pin JP, Liu J, Rondard P. Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer. https://www.nature.com/articles/s41467-019-10834-5#Sec23 Abstract G protein-coupled receptors (GPCRs) can integrate extracellular signals via allosteric interactions within dimers and higher-order [...]
GRANT. Project information. A PICS project (Project International de Coopération Scientifique, CNRS) has been granted to support Xavier Rovira's collaboration with the research group "Neurorécepteurs, dynamique et fonction" of the Institut de Génomique Fonctionnelle (IGF, Montpellier) and the group "Medicinal Chemistry & Synthesis" of the Centro de investigacion y desarrollo [...]
ARTICLE. Bossi, S., Helleringer, R., Galante, M., Monlleó, E., Trapero, A., Rovira, X., … McLean, H. (2018). A Light-Controlled Allosteric Modulator Unveils a Role for mGlu4 Receptors During Early Stages of Ischemia in the Rodent Cerebellar Cortex. Frontiers in Cellular Neuroscience, 12, 449. https://doi.org/10.3389/fncel.2018.00449 Abstract Metabotropic glutamate receptors (mGlus) are [...]
The leading international figures in the photopharmacology field met 1-2 November in Vic, at the second international symposium to be held on this emerging branch of science, which uses light to control the activity of medication. Around 130 people from universities and research centres in 15 different countries participated in [...]
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