Jaume Trapé Pujol
Coordinator of the Biomarkers and Mesothelial Pathophysiology research line in TR2Lab
ORCID: 0000-0003-4018-6906
Scientific Profile: URECERCA
Associate Professor in the Faculty of Medicine at the University of Vic-Central University of Catalonia (UVic-UCC).
He is a specialist in Clinical Biochemistry (1992) and Master in Clinical Biochemistry and Molecular Pathology Universitat Autonoma de Barcelona (1992) He developed his PhD with Dr Rafael Molina in the field of tumors markers (2004). Currently, He is the Head of Service of Laboratory Medicine at the Althaia Xarxa Assistencial Universitària de Manresa. He has expertise in biological variation and interpretation of change value and cancer biomarkers and their interpretation in serum and in body fluids.
My last happenings:
The diagnostic accuracy of HE4 in the differential diagnosis of pleural effusions.
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, la-Torre ND, Bosch-Presegué L, Otero-Viñas M, Catot S, Crespo-Casal M, Rives-Jimenez J, Arnau A, Costa R, Cugat JR, Gonzalez-Sánchez F, Pla-Salas X, Sant F. Clin Chim Acta. 2025 Jan 30;566:120027. doi:10.1016/j.cca.2024.120027 Read More Abstract Background: Pleural effusions are challenging to diagnose, with approximately 20-50% of malignant effusions not diagnosed by cytology. Human epididymal protein 4 (HE4) may be useful in the differential diagnosis of pleural effusions. In serum, this biomarker shows false-positive results in some benign diseases. The aim of this study was to evaluate the diagnostic utility [...]
Utility of human epididymis protein 4 in the differential diagnosis of ascites
Authors: Bérgamo S, Trapé J, González-García L, González-Fernández C, Vergara C, de-la-Torre N, Trujillo G, Estivill D, Álvarez-González MA, Bosch L, Otero-Viñas M, Bergós C, Catot S, Ruiz-Hidalgo D, Ros S, Sant F Clin Biochem. 2023 Oct;120:110645. doi:10.1016/j.clinbiochem.2023.110645. Read More Abstract Background and aims: Human epididymal protein 4 (HE4) may be a useful tool in the differential diagnosis of malignant ascites. The aim of this study was to evaluate the diagnostic utility of HE4 for detecting malignant ascites, taking into account the possible false positives identified with adenosine deaminase (ADA), C-reactive protein (CRP), % polynuclear cells (%PMN) and [...]
Lung cancer tumor markers in serous effusions and other body fluids
Article: Lung cancer tumor markers in serous effusions and other body fluids Authors: Jaume Trapé, Silvia Bérgamo, Laura González-Gracía, Carolina González-Fernández. Abstract: From its onset and during its progression, lung cancer may affect various extrapulmonary structures. These include the serous membranes, the pleura and pericardium, and less frequently the central nervous system, with leptomeningeal involvement. In these cases, fluid accumulates in the serous membranes which may contain substances secreted by the tumor. Measuring the concentrations of these substances can provide useful information for elucidating the origin of the fluid accumulation, either in pleural and pericardial effusions or in [...]
